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Multiple Myeloma

About Multiple Myeloma

Multiple myeloma is a cancer of plasma cells – a type of white blood cell found in the bone marrow. These cells normally produce antibodies to help fight infections, but in myeloma, they grow uncontrollably, crowding out healthy cells and producing abnormal proteins that can damage bones, kidneys and other organs. 

Over the past decade, treatment advances, particularly in cellular therapies, have led to higher response rates and longer survival for patients. 

For more resources, visit marybird.org/resources

Multiple Myeloma Screenings

Currently, there is no routine screening test for multiple myeloma in people without symptoms. 

However, early detection is key to improving treatment outcomes. Blood and urine tests, along with biopsies and imaging tests, are used to detect and monitor multiple myeloma in patients with symptoms or risk factors. 

Dr. Wood and patient

Risk Factors for Multiple Myeloma

  • Age: Most cases occur in people over 55. 
  • Gender: Men are slightly more likely to develop multiple myeloma. 
  • Race: Muliple myeloma is more than twice as common in Black people than White people. 
  • Family History: Having a close relative with myeloma increases risk. 
  • Radiation Exposure: Exposure to radiation or certain chemicals may increase your risk for developing myeloma. 

Symptoms of Multiple Myeloma

MOST COMMON WARNING SIGNS: 

  • Bone pain or weakness, especially in the back or ribs
  • Fatigue due to anemia 

OTHER SYMPTOMS INCLUDE: 

  • Frequent infections 
  • Low blood counts 
  • Impaired kidney function 
  • Hypercalcemia 

Advanced Treatment | Cellular Therapy Program

Mary Bird Perkins Cancer Center offers leading-edge therapies for multiple myeloma through our Myeloma, Lymphoma and Cellular Therapy Program, led by Andrew Dalovisio, M.D.

  • Bispecific T-cell Engager (BiTE) therapy- An injectable/infusional treatment that helps the immune system target and destroy myeloma cells 
  • Chimeric Antigen Receptor T-cell (CART) therapy- A personalized “boot camp” for the immune system, where a patient’s T-cells are engineered to find and kill myeloma cells. 

These therapies have proven highly effective, provide long-lasting remission for previously difficult-to-treat cancers, and in some cases, a potential cure. 

Mary Bird Perkins delivers these therapies in an outpatient setting, allowing patients to rest at home surrounded by loved ones instead of staying in the hospital. 

meet the doctor

Andrew Dalovisio, MD

Andrew Dalovisio, M.D.

Clinical Trials

Clinical trials are research studies that involve human beings in order to test new ways to prevent, detect, diagnose or treat diseases. A drug must be part of a clinical trial before the FDA will approve it to be put on the market. Oncology clinical trials are conducted in order to test new drugs or a new combination of drug treatments, new surgery and radiation therapies and new medical devices.

Every cancer center patient is evaluated for participation in a clinical trial. Those who meet the criteria to participate in clinical research receive a standard of care treatment, but with the added benefit of a trial that may enhance their outcomes.

If interested in volunteering to participate in a clinical research trial, or if you have concerns about the conduct of clinical research, please contact the Clinical Research office at (225) 215-1353, or by email at clinicalresearch@marybird.com.

Additional Support

  • American Cancer Society: The American Cancer Society website contains information on many aspects of cancer care geared toward patients and caregivers. 
  • National Cancer Institute: National Cancer Institute is a federal program that is part of the National Institutes of Health. It has resources and information for patients and caregivers which is based on scientific research. 
  • International Myeloma Foundation: This non-profit organization is dedicated to improving the quality of life of myeloma patients through support, education, advocacy and research.